The Warren County Sheriff's Department says a deputy was injured when he got into a fight with a man he was trying arrest.
More than half of the 159 victims were between 13 and 15 years old.
Just after 8:30 Friday morning, a deputy pulled over a car on I-65 at the 39 mile marker.
Police say they smelled marijuana in the car.
Deputies say both the driver, Reginald Williams, and passenger, Michael Groves, both of Chicago, IL admitted to smoking the drug.
Police searched Williams and found a large amount of cash.
While searching Groves, police say he resisted and a fight started.
Both men were arrested.
Police say Groves and the deputy were treated and released from the hospital.
They also found a large amount of pot, cash, and drug paraphernalia in the car, plus a baby bottle full of codeine.
Both men are in the Warren County Jail on multiple drug charges.