Central City police received a call just before nine o'clock Sunday morning of shots fired at 112 West 5th Street in Central City.
The caller advised them that a female at the residence was shot multiple times and the perpetrator was still on the scene and armed.
Upon arrival police officers placed Carl Watkins in custody and the weapon was secured on scene by the other officers.
The victim, Sara Watkins, was taken to the Muhlenberg Community Hospital where she died as a result from injuries in the shooting.
Carl Watkins was taken to the Muhlenberg County Detention Center and is charged with murder... domestic violence.
The investigation is ongoing.